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Shelly Xiong Selected Research

adefovir dipivoxil (Hepsera)

10/2008Antiviral effects of lamivudine, emtricitabine, adefovir dipivoxil, and tenofovir disoproxil fumarate administered orally alone and in combination to woodchucks with chronic woodchuck hepatitis virus infection.
1/2007In vitro susceptibility of adefovir-associated hepatitis B virus polymerase mutations to other antiviral agents.
1/2006Safety and efficacy of adefovir dipivoxil in patients infected with lamivudine-resistant hepatitis B and HIV-1.
6/2005Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B.
6/2004Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy.
12/2003Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre- and post-liver transplantation patients.
8/2003Resistance to adefovir dipivoxil therapy associated with the selection of a novel mutation in the HBV polymerase.
7/2003Week 48 resistance surveillance in two phase 3 clinical studies of adefovir dipivoxil for chronic hepatitis B.
2/2003Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B.
2/2003Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B.
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Shelly Xiong Research Topics

Disease

12Chronic Hepatitis B
01/2007 - 08/2002
4Infections
10/2008 - 08/2002
2Viremia
10/2008 - 07/2005
2Hepatitis B
01/2006 - 12/2003
1HIV Infections (HIV Infection)
07/2005
1Body Weight (Weight, Body)
07/2005
1Persistent Infection
06/2004
1Disease Progression
07/2003

Drug/Important Bio-Agent (IBA)

11adefovir dipivoxil (Hepsera)FDA Link
10/2008 - 08/2002
6Antiviral Agents (Antivirals)IBA
10/2008 - 02/2003
4Lamivudine (Epivir)FDA Link
10/2008 - 11/2003
3Tenofovir (Viread)FDA Link
10/2008 - 07/2005
3NucleosidesIBA
10/2008 - 07/2003
3NucleotidesIBA
07/2005 - 02/2003
3Hepatitis B e AntigensIBA
06/2005 - 02/2003
1Emtricitabine (Emtriva)FDA Link
10/2008
1RacivirIBA
10/2008
1ProTidesIBA
01/2007
1ProdrugsIBA
07/2006
1Pharmaceutical PreparationsIBA
07/2005
1Surface Antigens (Surface Antigen)IBA
07/2005
1AntigensIBA
07/2005
1Circular DNAIBA
06/2004
1adefovirIBA
07/2003
1DNA (Deoxyribonucleic Acid)IBA
02/2003
1Alanine Transaminase (SGPT)IBA
02/2003

Therapy/Procedure

7Therapeutics
10/2008 - 08/2002
2Oral Administration
10/2008 - 07/2005
1Liver Transplantation
12/2003